Transcriptional repression of CDKN2D by PML/RARα contributes to the altered proliferation and differentiation block of acute promyelocytic leukemia cells

Cell proliferation and differentiation are highly coordinated processes. These two processes are disrupted during leukemogenesis, resulting in differentiation block and uncontrolled proliferation in leukemia. To understand the mechanisms disrupting the coordination between the two processes in acute...

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Detalles Bibliográficos
Autores principales: Wang, Y, Jin, W, Jia, X, Luo, R, Tan, Y, Zhu, X, Yang, X, Wang, X, Wang, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649503/
https://www.ncbi.nlm.nih.gov/pubmed/25275592
http://dx.doi.org/10.1038/cddis.2014.388

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649503/
https://www.ncbi.nlm.nih.gov/pubmed/25275592
http://dx.doi.org/10.1038/cddis.2014.388

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