Seizure activity results in calcium- and mitochondria-independent ROS production via NADPH and xanthine oxidase activation

Seizure activity has been proposed to result in the generation of reactive oxygen species (ROS), which then contribute to seizure-induced neuronal damage and eventually cell death. Although the mechanisms of seizure-induced ROS generation are unclear, mitochondria and cellular calcium overload have...

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Detalles Bibliográficos
Autores principales: Kovac, S, Domijan, A-M, Walker, M C, Abramov, A Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649505/
https://www.ncbi.nlm.nih.gov/pubmed/25275601
http://dx.doi.org/10.1038/cddis.2014.390

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649505/
https://www.ncbi.nlm.nih.gov/pubmed/25275601
http://dx.doi.org/10.1038/cddis.2014.390

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