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Identification and characterization of the novel Col10a1 regulatory mechanism during chondrocyte hypertrophic differentiation

The majority of human skeleton develops through the endochondral pathway, in which cartilage-forming chondrocytes proliferate and enlarge into hypertrophic chondrocytes that eventually undergo apoptosis and are replaced by bone. Although at a terminal differentiation stage, hypertrophic chondrocytes...

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Detalles Bibliográficos
Autores principales: Gu, J, Lu, Y, Li, F, Qiao, L, Wang, Q, Li, N, Borgia, J A, Deng, Y, Lei, G, Zheng, Q
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649528/
https://www.ncbi.nlm.nih.gov/pubmed/25321476
http://dx.doi.org/10.1038/cddis.2014.444