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CTGF increases vascular endothelial growth factor-dependent angiogenesis in human synovial fibroblasts by increasing miR-210 expression

Connective tissue growth factor (CTGF, a.k.a. CCN2) is inflammatory mediator and abundantly expressed in osteoarthritis (OA). Angiogenesis is essential for OA progression. Here, we investigated the role of CTGF in vascular endothelial growth factor (VEGF) production and angiogenesis in OA synovial f...

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Detalles Bibliográficos
Autores principales: Liu, S-C, Chuang, S-M, Hsu, C-J, Tsai, C-H, Wang, S-W, Tang, C-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649533/
https://www.ncbi.nlm.nih.gov/pubmed/25341039
http://dx.doi.org/10.1038/cddis.2014.453