Caspase-9 mediates Puma activation in UCN-01-induced apoptosis

The protein kinase inhibitor 7-hydroxystaurosporine (UCN-01) is one of the most potent and frequently used proapoptotic stimuli. The BH3-only molecule of Bcl-2 family proteins has been reported to contribute to UCN-01-induced apoptosis. Here we have found that UCN-01 triggers Puma-induced mitochondr...

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Detalles Bibliográficos
Autores principales: Nie, C, Luo, Y, Zhao, X, Luo, N, Tong, A, Liu, X, Yuan, Z, Wang, C, Wei, Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649536/
https://www.ncbi.nlm.nih.gov/pubmed/25356864
http://dx.doi.org/10.1038/cddis.2014.461

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649536/
https://www.ncbi.nlm.nih.gov/pubmed/25356864
http://dx.doi.org/10.1038/cddis.2014.461

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