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High-resolution in-depth imaging of optically cleared thick samples using an adaptive SPIM

Today, Light Sheet Fluorescence Microscopy (LSFM) makes it possible to image fluorescent samples through depths of several hundreds of microns. However, LSFM also suffers from scattering, absorption and optical aberrations. Spatial variations in the refractive index inside the samples cause major ch...

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Detalles Bibliográficos
Autores principales: Masson, Aurore, Escande, Paul, Frongia, Céline, Clouvel, Grégory, Ducommun, Bernard, Lorenzo, Corinne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649629/
https://www.ncbi.nlm.nih.gov/pubmed/26576666
http://dx.doi.org/10.1038/srep16898