p53/PUMA expression in human pulmonary fibroblasts mediates cell activation and migration in silicosis

Phagocytosis of SiO(2) into the lung causes an inflammatory cascade that results in fibroblast proliferation and migration, followed by fibrosis. Clinical evidence has indicated that the activation of alveolar macrophages by SiO(2) produces rapid and sustained inflammation characterized by the gener...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Liu, Haijun, Dai, Xiaoniu, Fang, Shencun, Wang, Xingang, Zhang, Yingming, Yao, Honghong, Zhang, Xilong, Chao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649630/
https://www.ncbi.nlm.nih.gov/pubmed/26576741
http://dx.doi.org/10.1038/srep16900

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649630/
https://www.ncbi.nlm.nih.gov/pubmed/26576741
http://dx.doi.org/10.1038/srep16900

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