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Functional variants regulating LGALS1 (Galectin 1) expression affect human susceptibility to influenza A(H7N9)

The fatality of avian influenza A(H7N9) infection in humans was over 30%. To identify human genetic susceptibility to A(H7N9) infection, we performed a genome-wide association study (GWAS) involving 102 A(H7N9) patients and 106 heavily-exposed healthy poultry workers, a sample size critically restri...

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Detalles Bibliográficos
Autores principales: Chen, Yu, Zhou, Jie, Cheng, Zhongshan, Yang, Shigui, Chu, Hin, Fan, Yanhui, Li, Cun, Wong, Bosco Ho-Yin, Zheng, Shufa, Zhu, Yixin, Yu, Fei, Wang, Yiyin, Liu, Xiaoli, Gao, Hainv, Yu, Liang, Tang, Linglin, Cui, Dawei, Hao, Ke, Bossé, Yohan, Obeidat, Ma′en, Brandsma, Corry-Anke, Song, You-Qiang, To, Kelvin Kai-Wang, Sham, Pak Chung, Yuen, Kwok-Yung, Li, Lanjuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649671/
https://www.ncbi.nlm.nih.gov/pubmed/25687228
http://dx.doi.org/10.1038/srep08517