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Lipid droplets hypertrophy: a crucial determining factor in insulin regulation by adipocytes

Lipid droplets (LDs) hypertrophy in adipocytes is the main cause of energy metabolic system dysfunction, obesity and its afflictions such as T2D. However, the role of adipocytes in linking energy metabolic disorders with insulin regulation is unknown in humans. Human adipocytes constitutively synthe...

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Detalles Bibliográficos
Autores principales: Sanjabi, Bahram, Dashty, Monireh, Özcan, Behiye, Akbarkhanzadeh, Vishtaseb, Rahimi, Mehran, Vinciguerra, Manlio, van Rooij, Felix, Al-Lahham, Saad, Sheedfar, Fareeba, van Kooten, Theo G., Spek, C. Arnold, Rowshani, Ajda T., van der Want, Johannes, Klaassen, Rene, Sijbrands, Eric, Peppelenbosch, Maikel P., Rezaee, Farhad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649717/
https://www.ncbi.nlm.nih.gov/pubmed/25743104
http://dx.doi.org/10.1038/srep08816