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Tuftsin-derived T-peptide prevents cellular immunosuppression and improves survival rate in septic mice

The primary mechanisms of sepsis induced cellular immunesuppression involve immune dysfunction of T lymphocytes and negative immunoregulation of regulatory T cells (Tregs). It has been found that tuftsin is an immune modulating peptide derived from IgG in spleen. T-peptide is one of tuftsin analogs....

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Detalles Bibliográficos
Autores principales: Gao, Yu-Lei, Chai, Yan-Fen, Dong, Ning, Han, Su, Zhu, Xiao-Mei, Zhang, Qing-Hong, Yao, Yong-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649719/
https://www.ncbi.nlm.nih.gov/pubmed/26577833
http://dx.doi.org/10.1038/srep16725