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Tuftsin-derived T-peptide prevents cellular immunosuppression and improves survival rate in septic mice
The primary mechanisms of sepsis induced cellular immunesuppression involve immune dysfunction of T lymphocytes and negative immunoregulation of regulatory T cells (Tregs). It has been found that tuftsin is an immune modulating peptide derived from IgG in spleen. T-peptide is one of tuftsin analogs....
Autores principales: | Gao, Yu-Lei, Chai, Yan-Fen, Dong, Ning, Han, Su, Zhu, Xiao-Mei, Zhang, Qing-Hong, Yao, Yong-Ming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649719/ https://www.ncbi.nlm.nih.gov/pubmed/26577833 http://dx.doi.org/10.1038/srep16725 |
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