Identification of key amino acid residues responsible for internal and external pH sensitivity of Orai1/STIM1 channels

Changes of intracellular and extracellular pH are involved in a variety of physiological and pathological processes, in which regulation of the Ca(2+) release activated Ca(2+) channel (I(CRAC)) by pH has been implicated. Ca(2+) entry mediated by I(CRAC) has been shown to be regulated by acidic or al...

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Detalles Bibliográficos
Autores principales: Tsujikawa, Hiroto, Yu, Albert S, Xie, Jia, Yue, Zhichao, Yang, Wenzhong, He, Yanlin, Yue, Lixia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649748/
https://www.ncbi.nlm.nih.gov/pubmed/26576490
http://dx.doi.org/10.1038/srep16747

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649748/
https://www.ncbi.nlm.nih.gov/pubmed/26576490
http://dx.doi.org/10.1038/srep16747

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