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Identification of key amino acid residues responsible for internal and external pH sensitivity of Orai1/STIM1 channels
Changes of intracellular and extracellular pH are involved in a variety of physiological and pathological processes, in which regulation of the Ca(2+) release activated Ca(2+) channel (I(CRAC)) by pH has been implicated. Ca(2+) entry mediated by I(CRAC) has been shown to be regulated by acidic or al...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649748/ https://www.ncbi.nlm.nih.gov/pubmed/26576490 http://dx.doi.org/10.1038/srep16747 |