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Role of non-genomic androgen signalling in suppressing proliferation of fibroblasts and fibrosarcoma cells

The functions of androgen receptor (AR) in stromal cells are still debated in spite of the demonstrated importance of these cells in organ development and diseases. Here, we show that physiological androgen concentration (10 nM R1881 or DHT) fails to induce DNA synthesis, while it consistently stimu...

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Detalles Bibliográficos
Autores principales: Castoria, G, Giovannelli, P, Di Donato, M, Ciociola, A, Hayashi, R, Bernal, F, Appella, E, Auricchio, F, Migliaccio, A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649827/
https://www.ncbi.nlm.nih.gov/pubmed/25476896
http://dx.doi.org/10.1038/cddis.2014.497