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DNA methylation and differential gene regulation in photoreceptor cell death

Retinitis pigmentosa (RP) defines a group of inherited degenerative retinal diseases causing progressive loss of photoreceptors. To this day, RP is still untreatable and rational treatment development will require a thorough understanding of the underlying cell death mechanisms. Methylation of the D...

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Detalles Bibliográficos
Autores principales: Farinelli, P, Perera, A, Arango-Gonzalez, B, Trifunovic, D, Wagner, M, Carell, T, Biel, M, Zrenner, E, Michalakis, S, Paquet-Durand, F, Ekström, P A R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649831/
https://www.ncbi.nlm.nih.gov/pubmed/25476906
http://dx.doi.org/10.1038/cddis.2014.512