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Level of macroautophagy drives senescent keratinocytes into cell death or neoplastic evasion
Senescence is a non-proliferative state reached by normal cells in response to various stresses, including telomere uncapping, oxidative stress or oncogene activation. In previous reports, we have highlighted that senescent human epidermal keratinocytes have two opposite outcomes: either they die by...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649843/ https://www.ncbi.nlm.nih.gov/pubmed/25522271 http://dx.doi.org/10.1038/cddis.2014.533 |