Cargando…

Level of macroautophagy drives senescent keratinocytes into cell death or neoplastic evasion

Senescence is a non-proliferative state reached by normal cells in response to various stresses, including telomere uncapping, oxidative stress or oncogene activation. In previous reports, we have highlighted that senescent human epidermal keratinocytes have two opposite outcomes: either they die by...

Descripción completa

Detalles Bibliográficos
Autores principales: Deruy, E, Nassour, J, Martin, N, Vercamer, C, Malaquin, N, Bertout, J, Chelli, F, Pourtier, A, Pluquet, O, Abbadie, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649843/
https://www.ncbi.nlm.nih.gov/pubmed/25522271
http://dx.doi.org/10.1038/cddis.2014.533