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Tax contributes apoptosis resistance to HTLV-1-infected T cells via suppression of Bid and Bim expression
The human T-lymphotropic virus type 1 (HTLV-1) is the etiological agent of adult T-cell leukemia (ATL). HTLV-1 Tax has been shown to have a prosurvival role in infected T cells by enhancing expression of the Bcl-2 family of antiapoptotic proteins. In this study, we show that the expression of proapo...
Autores principales: | Mühleisen, A, Giaisi, M, Köhler, R, Krammer, P H, Li-Weber, M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649845/ https://www.ncbi.nlm.nih.gov/pubmed/25522269 http://dx.doi.org/10.1038/cddis.2014.536 |
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