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Biochemical nature of Russell Bodies

Professional secretory cells produce and release abundant proteins. Particularly in case of mutations and/or insufficient chaperoning, these can aggregate and become toxic within or amongst cells. Immunoglobulins (Ig) are no exception. In the extracellular space, certain Ig-L chains form fibrils cau...

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Detalles Bibliográficos
Autores principales: Francesca Mossuto, Maria, Ami, Diletta, Anelli, Tiziana, Fagioli, Claudio, Maria Doglia, Silvia, Sitia, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4649990/
https://www.ncbi.nlm.nih.gov/pubmed/26223695
http://dx.doi.org/10.1038/srep12585