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CD11c(+) monocyte/macrophages promote chronic Helicobacter hepaticus-induced intestinal inflammation through the production of IL-23

In inflammatory bowel diseases, a breakdown in host microbial interactions accompanies sustained activation of immune cells in the gut. Functional studies suggest a key role for interleukin-23 (IL-23) in orchestrating intestinal inflammation. IL-23 can be produced by various mononuclear phagocytes (...

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Detalles Bibliográficos
Autores principales: Arnold, I C, Mathisen, S, Schulthess, J, Danne, C, Hegazy, A N, Powrie, F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650208/
https://www.ncbi.nlm.nih.gov/pubmed/26242598
http://dx.doi.org/10.1038/mi.2015.65