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CD11c(+) monocyte/macrophages promote chronic Helicobacter hepaticus-induced intestinal inflammation through the production of IL-23
In inflammatory bowel diseases, a breakdown in host microbial interactions accompanies sustained activation of immune cells in the gut. Functional studies suggest a key role for interleukin-23 (IL-23) in orchestrating intestinal inflammation. IL-23 can be produced by various mononuclear phagocytes (...
Autores principales: | Arnold, I C, Mathisen, S, Schulthess, J, Danne, C, Hegazy, A N, Powrie, F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650208/ https://www.ncbi.nlm.nih.gov/pubmed/26242598 http://dx.doi.org/10.1038/mi.2015.65 |
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