An extended mini-complement factor H molecule ameliorates experimental C3 glomerulopathy

Abnormal regulation of the complement alternative pathway is associated with C3 glomerulopathy. Complement factor H is the main plasma regulator of the alternative pathway and consists of 20 short consensus repeat (SCR) domains. Although recombinant full-length factor H represents a logical treatmen...

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Detalles Bibliográficos
Autores principales: Nichols, Eva-Maria, Barbour, Thomas D, Pappworth, Isabel Y, Wong, Edwin K S, Palmer, Jeremy M, Sheerin, Neil S, Pickering, Matthew C, Marchbank, Kevin J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Basic Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650264/
https://www.ncbi.nlm.nih.gov/pubmed/26221753
http://dx.doi.org/10.1038/ki.2015.233

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650264/
https://www.ncbi.nlm.nih.gov/pubmed/26221753
http://dx.doi.org/10.1038/ki.2015.233

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