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The role of MCP-1-CCR2 ligand-receptor axis in chondrocyte degradation and disease progress in knee osteoarthritis

BACKGROUND: Osteoarthritis (OA) is a common arthritic disease and multifactorial whole-joint disease. Interactions of chemokines and OA is inadequately documented. RESULTS: In vivo and in vitro studies were conducted to investigate monocyte chemoattractant protein 1 (MCP-1) and receptor chemokine (C...

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Detalles Bibliográficos
Autores principales: Xu, Yuan-kun, Ke, Yan, Wang, Bin, Lin, Jian-hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650302/
https://www.ncbi.nlm.nih.gov/pubmed/26578310
http://dx.doi.org/10.1186/s40659-015-0057-0