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High fat plus high cholesterol diet lead to hepatic steatosis in zebrafish larvae: a novel model for screening anti-hepatic steatosis drugs

BACKGROUND: Non-alcoholic fatty liver disease (NAFLD), characterized as excessive lipid accumulation within hepatocytes, is growing in prevalence. The exploitation of effective drugs for NAFLD has been proven challenging. Herein, we aimed to establish a dietary model of hepatic steatosis using trans...

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Detalles Bibliográficos
Autores principales: Dai, Wencong, Wang, Kunyuan, Zheng, Xinchun, Chen, Xiaohui, Zhang, Wenqing, Zhang, Yiyue, Hou, Jinlin, Liu, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650307/
https://www.ncbi.nlm.nih.gov/pubmed/26583037
http://dx.doi.org/10.1186/s12986-015-0036-z