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Cartilage stem/progenitor cells are activated in osteoarthritis via interleukin-1β/nerve growth factor signaling
INTRODUCTION: Interleukin-1β (IL-1β) and nerve growth factor (NGF) are key regulators in the pathogenesis of inflammatory arthritis; specifically, IL-1β is involved in tissue degeneration and NGF is involved in joint pain. However, the cellular and molecular interactions between IL-1β and NGF in art...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650403/ https://www.ncbi.nlm.nih.gov/pubmed/26577823 http://dx.doi.org/10.1186/s13075-015-0840-x |