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Cartilage stem/progenitor cells are activated in osteoarthritis via interleukin-1β/nerve growth factor signaling

INTRODUCTION: Interleukin-1β (IL-1β) and nerve growth factor (NGF) are key regulators in the pathogenesis of inflammatory arthritis; specifically, IL-1β is involved in tissue degeneration and NGF is involved in joint pain. However, the cellular and molecular interactions between IL-1β and NGF in art...

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Detalles Bibliográficos
Autores principales: Jiang, Yangzi, Hu, Changchang, Yu, Shuting, Yan, Junwei, Peng, Hsuan, Ouyang, Hong Wei, Tuan, Rocky S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650403/
https://www.ncbi.nlm.nih.gov/pubmed/26577823
http://dx.doi.org/10.1186/s13075-015-0840-x