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Bone marrow-derived mesenchymal stem cells ameliorate chronic high glucose-induced β-cell injury through modulation of autophagy

Chronic hyperglycemia causes a progressive decrease of β-cell function and mass in type 2 diabetic patients. Growing evidence suggests that augment of autophagy may be an effective approach to protect β cells against various extra-/intracellular stimuli. In this study, we thus investigated whether b...

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Detalles Bibliográficos
Autores principales: Zhao, K, Hao, H, Liu, J, Tong, C, Cheng, Y, Xie, Z, Zang, L, Mu, Y, Han, W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650435/
https://www.ncbi.nlm.nih.gov/pubmed/26379190
http://dx.doi.org/10.1038/cddis.2015.230