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miR-449a targets Flot2 and inhibits gastric cancer invasion by inhibiting TGF-β-mediated EMT
BACKGROUND: Flot2, a highly conserved protein of the SPFH domain containing proteins family, has recently been identified as oncogene to be involved in the tumorigenesis and metastasis of several cancers including gastric cancer. However, the underlying molecular mechanism of Flot2 in gastric cancer...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650491/ https://www.ncbi.nlm.nih.gov/pubmed/26576674 http://dx.doi.org/10.1186/s13000-015-0435-5 |