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miR-449a targets Flot2 and inhibits gastric cancer invasion by inhibiting TGF-β-mediated EMT

BACKGROUND: Flot2, a highly conserved protein of the SPFH domain containing proteins family, has recently been identified as oncogene to be involved in the tumorigenesis and metastasis of several cancers including gastric cancer. However, the underlying molecular mechanism of Flot2 in gastric cancer...

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Detalles Bibliográficos
Autores principales: Li, Qian, Peng, Jie, Li, Xinhua, Leng, Aimin, Liu, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650491/
https://www.ncbi.nlm.nih.gov/pubmed/26576674
http://dx.doi.org/10.1186/s13000-015-0435-5