Thromboxane promotes smooth muscle phenotype commitment but not remodeling of hypoxic neonatal pulmonary artery

BACKGROUND: Persistent pulmonary hypertension of the newborn (PPHN) is characterized by vasoconstriction and pulmonary vascular remodeling. Remodeling is believed to be a response to physical or chemical stimuli including pro-mitotic inflammatory mediators such as thromboxane. Our objective was to e...

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Detalles Bibliográficos
Autores principales: Postolow, Fabiana, Fediuk, Jena, Nolette, Nora, Hinton, Martha, Dakshinamurti, Shyamala
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650498/
https://www.ncbi.nlm.nih.gov/pubmed/26583045
http://dx.doi.org/10.1186/s13069-015-0037-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650498/
https://www.ncbi.nlm.nih.gov/pubmed/26583045
http://dx.doi.org/10.1186/s13069-015-0037-6

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