Identification of RIP1 as a critical mediator of Smac mimetic-mediated sensitization of glioblastoma cells for Drozitumab-induced apoptosis

This study aims at evaluating the combination of the tumor-necrosis-factor-related apoptosis-inducing ligand (TRAIL)-receptor 2 (TRAIL-R2)-specific antibody Drozitumab and the Smac mimetic BV6 in preclinical glioblastoma models. To this end, the effect of BV6 and/or Drozitumab on apoptosis induction...

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Detalles Bibliográficos
Autores principales: Cristofanon, S, Abhari, B A, Krueger, M, Tchoghandjian, A, Momma, S, Calaminus, C, Vucic, D, Pichler, B J, Fulda, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650534/
https://www.ncbi.nlm.nih.gov/pubmed/25880091
http://dx.doi.org/10.1038/cddis.2014.592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650534/
https://www.ncbi.nlm.nih.gov/pubmed/25880091
http://dx.doi.org/10.1038/cddis.2014.592

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