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Alzheimer's disease-related amyloid-β induces synaptotoxicity in human iPS cell-derived neurons
Human induced pluripotent stem cell (iPSC)-derived neurons have been proposed to be a highly valuable cellular model for studying the pathomechanisms of Alzheimer's disease (AD). Studies employing patient-specific human iPSCs as models of familial and sporadic forms of AD described elevated lev...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650541/ https://www.ncbi.nlm.nih.gov/pubmed/25837485 http://dx.doi.org/10.1038/cddis.2015.72 |