Cargando…

Alzheimer's disease-related amyloid-β induces synaptotoxicity in human iPS cell-derived neurons

Human induced pluripotent stem cell (iPSC)-derived neurons have been proposed to be a highly valuable cellular model for studying the pathomechanisms of Alzheimer's disease (AD). Studies employing patient-specific human iPSCs as models of familial and sporadic forms of AD described elevated lev...

Descripción completa

Detalles Bibliográficos
Autores principales: Nieweg, K, Andreyeva, A, van Stegen, B, Tanriöver, G, Gottmann, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650541/
https://www.ncbi.nlm.nih.gov/pubmed/25837485
http://dx.doi.org/10.1038/cddis.2015.72