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Aberrant MEK5/ERK5 signalling contributes to human colon cancer progression via NF-κB activation

This study was designed to evaluate MEK5 and ERK5 expression in colon cancer progression and to ascertain the relevance of MEK5/ERK5 signalling in colon cancer. Expression of MEK5 and ERK5 was evaluated in 323 human colon cancer samples. To evaluate the role of MEK5/ERK5 signalling in colon cancer,...

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Detalles Bibliográficos
Autores principales: Simões, A E S, Pereira, D M, Gomes, S E, Brito, H, Carvalho, T, French, A, Castro, R E, Steer, C J, Thibodeau, S N, Rodrigues, C M P, Borralho, P M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650550/
https://www.ncbi.nlm.nih.gov/pubmed/25855966
http://dx.doi.org/10.1038/cddis.2015.83