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Oroxylin A inhibits glycolysis-dependent proliferation of human breast cancer via promoting SIRT3-mediated SOD2 transcription and HIF1α destabilization

Alterations of cellular metabolism play a central role in the development and progression of cancer. Oroxylin A, an active flavonoid of a Chinese traditional medicinal plant, was previously shown to modulate glycolysis in cancer cells. However, the mechanism by which oroxylin A regulates glycolysis...

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Detalles Bibliográficos
Autores principales: Wei, L, Zhou, Y, Qiao, C, Ni, T, Li, Z, You, Q, Guo, Q, Lu, N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650553/
https://www.ncbi.nlm.nih.gov/pubmed/25855962
http://dx.doi.org/10.1038/cddis.2015.86