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Oroxylin A inhibits glycolysis-dependent proliferation of human breast cancer via promoting SIRT3-mediated SOD2 transcription and HIF1α destabilization
Alterations of cellular metabolism play a central role in the development and progression of cancer. Oroxylin A, an active flavonoid of a Chinese traditional medicinal plant, was previously shown to modulate glycolysis in cancer cells. However, the mechanism by which oroxylin A regulates glycolysis...
Autores principales: | Wei, L, Zhou, Y, Qiao, C, Ni, T, Li, Z, You, Q, Guo, Q, Lu, N |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650553/ https://www.ncbi.nlm.nih.gov/pubmed/25855962 http://dx.doi.org/10.1038/cddis.2015.86 |
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