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GSK-3β-dependent downregulation of γ-taxilin and αNAC merge to regulate ER stress responses

The signaling pathway leading to the endoplasmic reticulum (ER) stress responses has not been fully elucidated. Here we showed that glycogen synthase kinase-3β (GSK-3β)-dependent downregulation of γ-taxilin and nascent polypeptide-associated complex α-subunit (αNAC) mediates hypoxia-induced unfolded...

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Detalles Bibliográficos
Autores principales: Hotokezaka, Y, Katayama, I, van Leyen, K, Nakamura, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650556/
https://www.ncbi.nlm.nih.gov/pubmed/25880086
http://dx.doi.org/10.1038/cddis.2015.90