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MAP3K3 expression in tumor cells and tumor-infiltrating lymphocytes is correlated with favorable patient survival in lung cancer

MAP3K3 is involved in both the immune response and in tumor progression. Its potential biological role in vitro in lung cancer cell lines and the association of mRNA/protein expression patterns with clinical outcome of primary lung tumors were investigated in this study. Silencing MAP3K3 using siRNA...

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Detalles Bibliográficos
Autores principales: He, Yanli, Wang, Lihui, Liu, Weijun, Zhong, Jinjie, Bai, Shengbin, Wang, Zhuwen, Thomas, Dafydd G., Lin, Jules, Reddy, Rishindra M., Ramnath, Nithya, Carrott, Philip W., Lynch, William R., Orringer, Mark B., Chang, Andrew C., Beer, David G., Chen, Guoan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650617/
https://www.ncbi.nlm.nih.gov/pubmed/26088427
http://dx.doi.org/10.1038/srep11471