G protein-coupled receptor 183 facilitates endothelial-to-hematopoietic transition via Notch1 inhibition

In vertebrates, embryonic hematopoietic stem and progenitor cells (HSPCs) are derived from a subset of endothelial cells, the hemogenic endothelium (HE), through the endothelial-to-hematopoietic transition (EHT). Notch signaling is essential for HSPC development during embryogenesis across vertebrat...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Panpan, He, Qiuping, Chen, Dongbo, Liu, Weixiao, Wang, Lu, Zhang, Chunxia, Ma, Dongyuan, Li, Wei, Liu, Bing, Liu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650626/
https://www.ncbi.nlm.nih.gov/pubmed/26358189
http://dx.doi.org/10.1038/cr.2015.109

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650626/
https://www.ncbi.nlm.nih.gov/pubmed/26358189
http://dx.doi.org/10.1038/cr.2015.109

Ejemplares similares