Ubiquitin-specific Protease 15 Negatively Regulates Virus-induced Type I Interferon Signaling via Catalytically-dependent and -independent Mechanisms

Viral infection triggers a series of signaling cascades, which converge to activate the transcription factors nuclear factor-κB (NF-κB) and interferon regulatory factor 3 (IRF3), thereby inducing the transcription of type I interferons (IFNs). Although not fully characterized, these innate antiviral...

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Detalles Bibliográficos
Autores principales: Zhang, Huan, Wang, Dang, Zhong, Huijuan, Luo, Rui, Shang, Min, Liu, Dezhi, Chen, Huanchun, Fang, Liurong, Xiao, Shaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650652/
https://www.ncbi.nlm.nih.gov/pubmed/26061460
http://dx.doi.org/10.1038/srep11220

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650652/
https://www.ncbi.nlm.nih.gov/pubmed/26061460
http://dx.doi.org/10.1038/srep11220

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