Preparation by alkaline treatment and detailed characterisation of empty hepatitis B virus core particles for vaccine and gene therapy applications

Hepatitis B virus (HBV) core (HBc) virus-like particles (VLPs) are one of the most powerful protein engineering tools utilised to expose immunological epitopes and/or cell-targeting signals and for the packaging of genetic material and immune stimulatory sequences. Although HBc VLPs and their numero...

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Detalles Bibliográficos
Autores principales: Strods, Arnis, Ose, Velta, Bogans, Janis, Cielens, Indulis, Kalnins, Gints, Radovica, Ilze, Kazaks, Andris, Pumpens, Paul, Renhofa, Regina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650659/
https://www.ncbi.nlm.nih.gov/pubmed/26113394
http://dx.doi.org/10.1038/srep11639

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650659/
https://www.ncbi.nlm.nih.gov/pubmed/26113394
http://dx.doi.org/10.1038/srep11639

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