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The structure of the folded domain from the signature multifunctional protein ICP27 from herpes simplex virus-1 reveals an intertwined dimer

Herpesviruses cause life-long infections by evading the host immune system and establishing latent infections. All mammalian herpesviruses express an essential multifunctional protein that is typified by ICP27 encoded by Herpes Simplex Virus 1. The only region that is conserved among the diverse mem...

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Detalles Bibliográficos
Autores principales: Tunnicliffe, Richard B., Schacht, Mitchell, Levy, Colin, Jowitt, Thomas A., Sandri-Goldin, Rozanne M., Golovanov, Alexander P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650695/
https://www.ncbi.nlm.nih.gov/pubmed/26062451
http://dx.doi.org/10.1038/srep11234