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The structure of the folded domain from the signature multifunctional protein ICP27 from herpes simplex virus-1 reveals an intertwined dimer
Herpesviruses cause life-long infections by evading the host immune system and establishing latent infections. All mammalian herpesviruses express an essential multifunctional protein that is typified by ICP27 encoded by Herpes Simplex Virus 1. The only region that is conserved among the diverse mem...
Autores principales: | Tunnicliffe, Richard B., Schacht, Mitchell, Levy, Colin, Jowitt, Thomas A., Sandri-Goldin, Rozanne M., Golovanov, Alexander P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650695/ https://www.ncbi.nlm.nih.gov/pubmed/26062451 http://dx.doi.org/10.1038/srep11234 |
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