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Novel anti-thrombotic agent for modulation of protein disulfide isomerase family member ERp57 for prophylactic therapy

Protein disulfide isomerase (PDI) family members including PDI and ERp57 emerge as novel targets for anti-thrombotic treatments, but chemical agents with selectivity remain to be explored. We previously reported a novel derivative of danshensu (DSS), known as ADTM, displayed strong cardioprotective...

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Detalles Bibliográficos
Autores principales: Cui, Guozhen, Shan, Luchen, Guo, Lin, Chu, Ivan Keung, Li, Guohui, Quan, Quan, Zhao, Yun, Chong, Cheong Meng, Zhang, Zaijun, Yu, Pei, Hoi, Maggie Pui Man, Sun, Yewei, Wang, Yuqiang, Lee, Simon MingYuen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650696/
https://www.ncbi.nlm.nih.gov/pubmed/26037049
http://dx.doi.org/10.1038/srep10353