LincHOTAIR epigenetically silences miR34a by binding to PRC2 to promote the epithelial-to-mesenchymal transition in human gastric cancer

lncRNAs play important roles in the epigenetic regulation of carcinogenesis and progression. Previous studies suggest that HOTAIR contributes to gastric cancer (GC) development, and the overexpression of HOTAIR predicts a poor prognosis. In this study, we found that HOTAIR was more highly expressed...

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Detalles Bibliográficos
Autores principales: Liu, Y-w, Sun, M, Xia, R, Zhang, E-b, Liu, X-h, Zhang, Z-h, Xu, T-p, De, W, Liu, B-r, Wang, Z-x
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650715/
https://www.ncbi.nlm.nih.gov/pubmed/26136075
http://dx.doi.org/10.1038/cddis.2015.150

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650715/
https://www.ncbi.nlm.nih.gov/pubmed/26136075
http://dx.doi.org/10.1038/cddis.2015.150

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