Aggregated α-synuclein and complex I deficiency: exploration of their relationship in differentiated neurons

α-Synuclein becomes misfolded and aggregated upon damage by various factors, for example, by reactive oxygen species. These aggregated forms have been proposed to have differential toxicities and their interaction with mitochondria may cause dysfunction within this organelle that contributes to the...

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Detalles Bibliográficos
Autores principales: Reeve, A K, Ludtmann, M HR, Angelova, P R, Simcox, E M, Horrocks, M H, Klenerman, D, Gandhi, S, Turnbull, D M, Abramov, A Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650719/
https://www.ncbi.nlm.nih.gov/pubmed/26181201
http://dx.doi.org/10.1038/cddis.2015.166

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650719/
https://www.ncbi.nlm.nih.gov/pubmed/26181201
http://dx.doi.org/10.1038/cddis.2015.166

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