Genome-editing tools for stem cell biology

Human pluripotent stem cells provide a versatile platform for regenerative studies, drug testing and disease modeling. That the expression of only four transcription factors, Oct4, Klf4, Sox2 and c-Myc (OKSM), is sufficient for generation of induced pluripotent stem cells (iPSCs) from differentiated...

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Detalles Bibliográficos
Autores principales: Vasileva, E A, Shuvalov, O U, Garabadgiu, A V, Melino, G, Barlev, N A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650720/
https://www.ncbi.nlm.nih.gov/pubmed/26203860
http://dx.doi.org/10.1038/cddis.2015.167

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650720/
https://www.ncbi.nlm.nih.gov/pubmed/26203860
http://dx.doi.org/10.1038/cddis.2015.167

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