Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons

Many neuropathological and experimental studies suggest that the degeneration of dopaminergic terminals and axons precedes the demise of dopaminergic neurons in the substantia nigra, which finally results in the clinical symptoms of Parkinson disease (PD). The mechanisms underlying this early axonal...

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Detalles Bibliográficos
Autores principales: Koch, J C, Bitow, F, Haack, J, d'Hedouville, Z, Zhang, J-N, Tönges, L, Michel, U, Oliveira, L M A, Jovin, T M, Liman, J, Tatenhorst, L, Bähr, M, Lingor, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650722/
https://www.ncbi.nlm.nih.gov/pubmed/26158517
http://dx.doi.org/10.1038/cddis.2015.169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650722/
https://www.ncbi.nlm.nih.gov/pubmed/26158517
http://dx.doi.org/10.1038/cddis.2015.169

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