Loss of apoptosis-inducing factor critically affects MIA40 function

Mitochondrial apoptosis-inducing factor (AIF) influences the oxidative phosphorylation (OXPHOS) system and can be recruited as a mediator of cell death. Pathogenic mutations in the AIFM1 gene cause severe human diseases. Clinical manifestations include inherited peripheral neuropathies, prenatal cer...

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Detalles Bibliográficos
Autores principales: Meyer, K, Buettner, S, Ghezzi, D, Zeviani, M, Bano, D, Nicotera, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650723/
https://www.ncbi.nlm.nih.gov/pubmed/26158520
http://dx.doi.org/10.1038/cddis.2015.170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650723/
https://www.ncbi.nlm.nih.gov/pubmed/26158520
http://dx.doi.org/10.1038/cddis.2015.170

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