Role of acid sphingomyelinase bioactivity in human CD4(+) T-cell activation and immune responses

Acid sphingomyelinase (ASM), a lipid hydrolase enzyme, has the potential to modulate various cellular activation responses via the generation of ceramide and by interaction with cellular receptors. We have hypothesized that ASM modulates CD4(+) T-cell receptor activation and impacts immune responses...

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Detalles Bibliográficos
Autores principales: Bai, A, Kokkotou, E, Zheng, Y, Robson, S C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650726/
https://www.ncbi.nlm.nih.gov/pubmed/26203857
http://dx.doi.org/10.1038/cddis.2015.178

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650726/
https://www.ncbi.nlm.nih.gov/pubmed/26203857
http://dx.doi.org/10.1038/cddis.2015.178

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