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Role of acid sphingomyelinase bioactivity in human CD4(+) T-cell activation and immune responses
Acid sphingomyelinase (ASM), a lipid hydrolase enzyme, has the potential to modulate various cellular activation responses via the generation of ceramide and by interaction with cellular receptors. We have hypothesized that ASM modulates CD4(+) T-cell receptor activation and impacts immune responses...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4650726/ https://www.ncbi.nlm.nih.gov/pubmed/26203857 http://dx.doi.org/10.1038/cddis.2015.178 |